Potassium Carbonate → HCID 22568991, 화합물

HRID 278805노트

반응식

HRID 278805 반응식
[CH:1]1([N:4]([CH2:19][CH3:20])[CH2:5][C:6]2[CH:11]=[CH:10][C:9]([C:12]#[C:13][Si](C)(C)C)=[CH:8][C:7]=2[CH3:18])[CH2:3][CH2:2]1.C(=O)([O-])[O-].[K+].[K+]>CO>[CH:1]1([N:4]([CH2:19][CH3:20])[CH2:5][C:6]2[CH:11]=[CH:10][C:9]([C:12]#[CH:13])=[CH:8][C:7]=2[CH3:18])[CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 22568965Cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine2회

생성물 1

HCID 22568991HCID 22568991, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Using General Procedure E; cyclopropyl-ethyl-(2-methyl-4-trimethylsilanylethynyl-benzyl)-amine (Intermediate 160, 650.0 mg, 2.30 mmols) in methanol (10 mL) was treated with potassium carbonate (100.0 mg, 0.72 mmol) and stirred overnight at ambient temperature. The crude alkyne (495 mg, 99%) was used directly in the next reaction.

출처 및 근거

ORD 기록
ord-7722ac89ab2a4ab9b757da9a848f4a44
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06359135B1

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