Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Bromide → 2-Ethoxybenzonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Bromide | HCID 6332 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Hydroxybenzonitrile | HCID 11907 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Ethoxybenzonitrile | HCID 576922 | — |
반응 단계
25 g (210 mmol) of 2-hydroxybenzonitrile are refluxed with 87 g of potassium carbonate and 34.3 g (314.8 mmol) of ethyl bromide in 500 ml of acetone overnight. The solid is filtered off, the solvent is removed under reduced pressure and the residue is distilled under reduced pressure. This gives 30.0 g (97%) of a colourless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06362178B1 |
| 출처 데이터셋 | uspto-grants-2002_03 |
| ORD ID | ord-258562bd70ed4afcb0092731ff403957 |
| 출처 메모 | uspto-grants-2002_03 |