Benzyloxyamine hydrochloride → 2-Benzyloxy-5-bromo-benzo[de]isoquinoline-1,3-dione

HRID 278957

반응식

HRID 278957 반응식
Cl.[CH2:2]([O:9][NH2:10])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH:11]1[CH:20]=[C:19]2[C:21]([O:23][C:24](=O)[C:17]3=[C:18]2[C:13](=[CH:14][C:15]([Br:26])=[CH:16]3)[CH:12]=1)=[O:22]>N1C=CC=CC=1>[CH2:2]([O:9][N:10]1[C:24](=[O:23])[C:17]2[CH:16]=[C:15]([Br:26])[CH:14]=[C:13]3[C:18]=2[C:19](=[CH:20][CH:11]=[CH:12]3)[C:21]1=[O:22])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

참가 물질

4

반응물 2

HCID 102312Benzyloxyamine hydrochlorideHCID 39074915-Bromobenzo[de]isochromene-1,3-dione

생성물 1

HCID 226238992-Benzyloxy-5-bromo-benzo[de]isoquinoline-1,3-dione수율 89.1%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

O-Benzyl hydroxylamine hydrochloride (0.9 g, 5.6 mmol) and 3-bromo-1,8-naphthalic anhydride (1.3 g, 4.7 mmol, from Example N) were reacted in pyridine (30 mL) following the procedure of Example D to give 1.6 g of the title compound.

출처 및 근거

ORD 기록
ord-ad7983d3103e46e089e443e7cda907fc
출처 데이터셋
uspto-grants-2002_03
특허 번호
US06362181B1

연결된 노트

불러오는 중…