Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → N-(3,5-Dichloropyridin-2-yl)-N'-methylthiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | 3,5-Dichloro-2-isothiocyanatopyridine | HCID 23340445 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-(3,5-Dichloropyridin-2-yl)-N'-methylthiourea | HCID 23340446 | — |
반응 단계
A solution of 3,5 dichloro-2-pyridylisothiocyanate (5.13 g.) in benzene (20 ml.) was added to a solution of methylamine in ethanol (5 ml., 33%) and the mixture was stirred for 18 hours at ambient temperature. Petroleum ether (60°-80° C., 30 ml.) was added and the resulting precipitate was filtered off and recrystallised from benzene-light petroleum to give colourless microcrystals of 1-(3,5-dichloro-2-pyridyl)-3-methyl-2-thiourea (4.18 g.) m.pt. 105°-109° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04224331 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-447b26ef6ea94b23ada5e0d8ac45c4d5 |
| 출처 메모 | uspto-grants-1980_09 |