참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Succinic anhydride | HCID 7922 | — |
| 반응물 | Tetrahydrofuran | HCID 8028 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methyl thyroxinate hydrochloride | HCID 13911220 | — |
| 생성물 | Thyroxine | HCID 5819 | — |
반응 단계
In 150 ml of dried tetrahydrofuran 1.65 g (0.002 mol) of thyroxine methyl ester hydrochloride was dissolved. To the resulting solution 300 μl (0.0021 mol) of triethyl amine and 200 mg. (0.0022 mol) of succinic anhydride were added. The mixture was stirred at 4° C. overnight to effect reaction.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04587102 |
|---|
| 출처 데이터셋 | uspto-grants-1986_05 |
|---|
| ORD ID | ord-d6e33fbb8e70494a89adc8bd3b8100b1 |
|---|
| 출처 메모 | uspto-grants-1986_05 |
|---|
