Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → Methylprednisolone Aceponate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Methylprednisolone 17-Propionate | HCID 10025718 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 생성물 | Methylprednisolone Aceponate | HCID 63019 | — |
반응 단계
Analogously to Example 1, 1.0 g of 11β,21-dihydroxy-6α-methyl-17-propionyloxy-1,4-pregnadiene-3,20-dione is stirred in 10 ml of pyridine with 5 ml of acetic anhydride for one hour at room temperature and then worked up, thus isolating 790 mg of 21-acetoxy-11β-hydroxy-6α-methyl-17-propionyloxy-1,4-pregnadiene-3,20-dione, mp 138° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04587236 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-759df690686e4bae8fe7d3dd8ac9ca11 |
| 출처 메모 | uspto-grants-1986_05 |