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HRID 279834생성일: 2026년 10월 26일

2-Chloro-4-nitropyridine 1-oxide → Pyridine, 2-chloro-4-methoxy-, 1-oxide

https://huagongshe.com/reaction/279834

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-4-nitropyridine 1-oxideHCID 84433—
반응물SodiumHCID 5360545—
반응물Sodium MethoxideHCID 10942334—
용매MethanolHCID 887—
생성물Pyridine, 2-chloro-4-methoxy-, 1-oxideHCID 15593755—

반응 단계

Sodium (0.46 g) is dissolved in absolute methanol (50 ml) and the resultant solution of sodium methoxide is added to a solution of 2-chloro-4-nitropyridine-1-oxide (3.5 g, prepared as described in Example 1) in methanol (10 ml). The reaction mixture is allowed to stand at room temperature for 50 hours and is then subjected to rotary evaporation to give 2-chloro-4-methoxypyridine-1-oxide.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04587240
출처 데이터셋uspto-grants-1986_05
ORD IDord-20c5b2c1ecd64b7c88f1f08ccc54e6e7
출처 메모uspto-grants-1986_05