Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | HCID 13755631 | HCID 13755631 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 2-Thiophenecarboxylic acid, 3-(chlorosulfonyl)-, methyl ester | HCID 2736733 | — |
반응 단계
48 G. (0.196 mol) of the obtained 3-chlorosulfonylthiophene-2-carboxylic acid chloride are dissolved in 500 ml. of absolute chloroform, 9.6 g. (0.3 mol) of absolute methanol are added and the mixture is heated to reflux for 3 hours [until no more hydrogen chloride evolution]. The mixture is evaporated to dryness in vacuo and the residue allowed to crystallize. There is obtained pure 3-chlorosulfonylthiophene-2-carboxylic acid methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04224445 |
| 출처 데이터셋 | uspto-grants-1980_09 |
| ORD ID | ord-e5450b14b448460e832d4776e5571568 |
| 출처 메모 | uspto-grants-1980_09 |