Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → N-(3-hydroxypropyl)-2,3,4-trimethoxy-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | 3-Amino-1-propanol | HCID 9086 | — |
| 반응물 | 2,3,4-trimethoxybenzenesulfonyl Chloride | HCID 4712742 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-(3-hydroxypropyl)-2,3,4-trimethoxy-benzenesulfonamide | HCID 13645632 | — |
반응 단계
2,3,4-Trimethoxybenzene sulfonyl chloride (20.4 g, 0.765 m) in methylene chloride (100 ml) was added dropwise to 3-aminopropanol (17.2 g) in methylene chloride (300 ml). After stirring overnight the reaction was washed with dilute aqueous HCl, dried and stripped to provide a solid. Trituration with diethyl ether provided the product N-(3-hydroxypropyl)-2,3,4-trimethoxy-benzenesulfonamide, m.p. 95°-97° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04587360 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-2a8de3b233524fb4987aa632861c0049 |
| 출처 메모 | uspto-grants-1986_05 |