Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitrophenol → Diethyl[2-(4-nitrophenoxy)ethyl]amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitrophenol | HCID 980 | — |
| 반응물 | Diethylaminoethyl chloride | HCID 13364 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Diethyl[2-(4-nitrophenoxy)ethyl]amine | HCID 88294 | — |
반응 단계
To a cold solution of 41.8 g of 4-nitrophenol in 250 ml of DMF was added 16.0 g of a 57% dispersion of sodium hydride in mineral oil, followed by 46.0 g of 2-diethylaminoethyl chloride. After 20 hours, the mixture was filtered, freed of solvent by evaporation under reduced pressure, the residue dissolved in ether and washed with water. Extraction with 2N hydrochloric acid and basification of the extract gave N,N-diethyl-2-(4-nitrophenoxy)ethanamine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588730 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-8642a758cc744568a9c3812c649ac4ca |
| 출처 메모 | uspto-grants-1986_05 |