Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Amino-1-(3-fluorophenyl)ethan-1-ol → HCID 23322168, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Amino-1-(3-fluorophenyl)ethan-1-ol | HCID 35800 | — |
| 반응물 | Fumaric Acid | HCID 444972 | — |
| 반응물 | 2-Amino-1-(3-chlorophenyl)ethan-1-ol | HCID 3751601 | — |
| 생성물 | HCID 23322168 | HCID 23322168 | — |
반응 단계
The title compound was prepared in the manner described in Example 3 replacing 2-(3-chlorophenyl)-2-hydroxyethanamine with 2-(3-fluorophenyl)-2-hydroxyethanamine. The chromatographed material was treated with methanolic fumaric acid and the derived salt recrystallised from ethyl acetate to give the title compound (fumarate), mp 58-83, as a 52-48 mixture of diastereoisomers.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04588749 |
| 출처 데이터셋 | uspto-grants-1986_05 |
| ORD ID | ord-cae322d37bd94ec9aae0e1baf9fe6a28 |
| 출처 메모 | uspto-grants-1986_05 |