Diethyl Ether → HCID 54258967, 화합물

HRID 280435노트

반응식

HRID 280435 반응식
CO[NH:3][CH3:4].[N:5]([C:8]1[CH:23]=[CH:22][C:11]([O:12][C:13]2[CH:14]=[CH:15][C:16]3[S:20][N:19]=[CH:18][C:17]=3[CH:21]=2)=[CH:10][CH:9]=1)=[C:6]=[O:7].C([O:26][CH2:27]C)C>>[CH3:27][O:26][N:5]([C:8]1[CH:23]=[CH:22][C:11]([O:12][C:13]2[CH:14]=[CH:15][C:16]3[S:20][N:19]=[CH:18][C:17]=3[CH:21]=2)=[CH:10][CH:9]=1)[C:6]([NH:3][CH3:4])=[O:7]

참가 물질

4

반응물 3

HCID 3283Diethyl EtherHCID 14232N,O-DimethylhydroxylamineHCID 132693995-(4-Isocyanatophenoxy)-1,2-benzothiazole

생성물 1

HCID 54258967HCID 54258967, 화합물수율 82%

실험 절차

6.1 parts of N-methoxy-N-methylamine were added to a solution of 26.8 parts of 5-(4'-isocyanatophenoxy)-benzisothiazole in 300 parts of diethyl ether at from 20° to 30° C., the mixture was stirred for 12 hours at this temperature and then evaporated down, and the residue was triturated in about 50 parts of diethyl ether, isolated and dried. 26 g (82% of theory) of 5-(4'-(N-methoxy-N-methylaminocarbonylamino)-phenoxy)-benzisothiazole of melting point 108° C. were obtained.

후처리

  1. customevaporated down
  2. customthe residue was triturated in about 50 parts of diethyl ether
  3. customisolated
  4. customdried

출처 및 근거

ORD 기록
ord-0df38d2b8ecf40e09ef4a1a51bd7b446
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04589910

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