Phosphorus pentachloride → 3-Methoxy-2,2,3,3-tetrafluoropropionyl chloride

반응식

[CH3:1][O:2][C:3]([F:11])([F:10])[C:4]([F:9])([F:8])[C:5](O)=[O:6].P(Cl)(Cl)(Cl)(Cl)[Cl:13]>>[CH3:1][O:2][C:3]([F:11])([F:10])[C:4]([F:9])([F:8])[C:5]([Cl:13])=[O:6]

참가 물질

반응물 2

HCID 24819Phosphorus pentachloride

HCID 133289072,2,3,3-Tetrafluoro-3-methoxypropanoic acid

생성물 1

HCID 128460263-Methoxy-2,2,3,3-tetrafluoropropionyl chloride수율 95.2%

실험 절차

A mixture of 47.4 g 3-methoxytetrafluoropropionic acid and 67.3 g phosphorous pentachloride was heated and the contents distilled to obtain a pale yellow liquid boiling to 102°. Redistillation of this liquid yielded 49.8 g (95.2%) 3-methoxytetrafluoropropionyl chloride, b.p. 84°-86°.

후처리

temperaturewas heated
distillationthe contents distilled
customto obtain a pale yellow liquid boiling to 102°
distillationRedistillation of this liquid

출처 및 근거

ORD 기록: ord-fa8f90a5a9564181ae90cf68447d915a
출처 데이터셋: uspto-grants-1986_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04590015

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