Glutaric anhydride → Theophylline

HRID 28064

반응식

HRID 28064 반응식
[NH2:1][C:2]1[N:3]([CH3:12])[C:4](=[O:11])[N:5]([CH3:10])[C:6](=[O:9])[C:7]=1[NH2:8].[C:13]1(=O)OC(=O)CCC1>>[N:5]1([C:6](=[O:9])[C:7]2[NH:8][CH:13]=[N:1][C:2]=2[N:3]([CH3:12])[C:4]1=[O:11])[CH3:10]

참가 물질

3

반응물 2

HCID 7940Glutaric anhydrideHCID 795015,6-Diamino-1,3-dimethyluracil

생성물 1

HCID 2153Theophylline

실험 절차

Following the method of Cook et al, Res. Comm. Chem. Path. Pharm. 13:497(1976), 4,5-diamino-1,3-dimethylpyrimidine-2,6-dione is heated with glutaric anhydride to yield the following: ##STR12##

후처리

  1. customto yield the following: ##STR12##

출처 및 근거

ORD 기록
ord-a11fefbd31c743d89293b71722a413e5
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04225485

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