Tetrahydrofuran → HCID 178467223, 화합물

HRID 280746노트

반응식

HRID 280746 반응식
[CH3:1][C:2]1[N:3](C(=O)C)[CH:4]=[CH:5][N:6]=1.[O:10]1CC[CH2:12][CH2:11]1>>[CH3:1][C:2]1[NH:6][CH:5]=[C:4]([C:11](=[O:10])[CH3:12])[N:3]=1

참가 물질

3

반응물 2

HCID 8028TetrahydrofuranHCID 130588401-(2-Methyl-1-imidazolyl)ethanone

생성물 1

HCID 178467223HCID 178467223, 화합물수율 45%

실험 절차

5.75 g (46.3 mmol) of 1-(2-methyl-1-imidazolyl)-ethanone was dissolved in 600 ml tetrahydrofuran and photolyzed in a quartz flask with a short wave u.v. light source (2537 nm) for 18 hours. The tetrahydrofuran solution was concentrated in vacuo to an oil and chromatographed on silica gel using 5% methanol in chloroform as eluent to give 2.6 g (45%) 1(2-methyl-4-imidazolyl)ethanone, mp 123°-5°.

후처리

  1. customphotolyzed in a quartz flask with a short wave u.v
  2. concentrationThe tetrahydrofuran solution was concentrated in vacuo to an oil
  3. customchromatographed on silica gel using 5% methanol in chloroform as eluent

출처 및 근거

ORD 기록
ord-87aba66381f647dc9a5b90504cdf48b1
출처 데이터셋
uspto-grants-1986_05
특허 번호
US04590299

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