Trimethyl phosphite → Benzyl dimethoxy(oxo)-lambda~5~-phosphanecarboxylate

반응식

C[O:2][P:3]([O:6][CH3:7])[O:4][CH3:5].Cl[C:9]([O:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:10]>>[CH2:12]([O:11][C:9]([P:3](=[O:2])([O:6][CH3:7])[O:4][CH3:5])=[O:10])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

참가 물질

반응물 2

HCID 8472Trimethyl phosphite

HCID 10387Benzyl chloroformate

생성물 1

HCID 512106Benzyl dimethoxy(oxo)-lambda~5~-phosphanecarboxylate

실험 절차

From 50 ml (0.4 mole) of trimethylphosphite and 56.9 g (0.3 mole) of benzyl chloroformate (Sigma 90-95%) (100° C., 2 hours). Yield 73 g (90%). Bp0.02 135°-6° C. nD25 1,4997.

후처리

customBp0.02 135°-6° C.

출처 및 근거

ORD 기록: ord-e384d9de3dcf47158dc942a04a929ee8
출처 데이터셋: uspto-grants-1986_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04591583

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