Ammonia → Cyromazine

HRID 28111

반응식

HRID 28111 반응식
[CH:1]1([NH:4][C:5]2[N:10]=[C:9](Cl)[N:8]=[C:7]([NH2:12])[N:6]=2)[CH2:3][CH2:2]1.[NH3:13]>O1CCOCC1>[CH:1]1([NH:4][C:5]2[N:10]=[C:9]([NH2:13])[N:8]=[C:7]([NH2:12])[N:6]=2)[CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 233389806-Chloro-N~2~-cyclopropyl-1,3,5-triazine-2,4-diamine

생성물 1

HCID 47866Cyromazine수율 55.8%

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

반응 조건

온도
140 °C

실험 절차

A mixture of 100 g of 2-cyclopropylamino-4-chloro-6-amino-s-triazine, 51 g of anhydrous ammonia and 500 ml of dioxane is heated for 24 hours in an autoclave at 140° C. After cooling to room temperature the solvent is removed by water jet vacuum distillation. 300 ml of water are added to the residue. After stirring, the residue product is filtered off and recrystallised from boiling ethanol. 50 g of 2-cyclopropylamino-4,6-diamino-s-triazine are obtained. Melting point: 219°-222° C.

후처리

  1. temperatureAfter cooling to room temperature the solvent
  2. customis removed by water jet vacuum distillation
  3. addition300 ml of water are added to the residue
  4. filtrationthe residue product is filtered off
  5. customrecrystallised

출처 및 근거

ORD 기록
ord-1ea168a6fd874ae1beb21deef9846912
출처 데이터셋
uspto-grants-1980_09
특허 번호
US04225598

연결된 노트

불러오는 중…