Tetrahydrofuran → 4-Benzyloxy-1-{2-oxo-2-[2-(2,2,2-trifluoro-acetyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-ethyl}-1H-pyridin-2-one

HRID 281785

반응식

HRID 281785 반응식
[C:17]([NH3+:18])([CH3:19])([CH3:20])[CH3:21].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[nH:12][cH:13][cH:14]1.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[Cl:22][CH2:23][C:24](=[O:25])[c:26]1[cH:27][cH:28][c:29]2[c:34]([cH:35]1)[CH2:33][N:32]([C:36]([C:37]([F:38])([F:39])[F:40])=[O:41])[CH2:31][CH2:30]2.[I-:16]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11](=[O:15])[n:12]([CH2:23][C:24](=[O:25])[c:26]2[cH:27][cH:28][c:29]3[c:34]([cH:35]2)[CH2:33][N:32]([C:36]([C:37]([F:38])([F:39])[F:40])=[O:41])[CH2:31][CH2:30]3)[cH:13][cH:14]1

참가 물질

7

반응물 6

HCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 30165Iodide IonHCID 36077244-Benzyloxy-2(1H)-pyridoneHCID 3833866Tert-butylammoniumHCID 866236881-[7-(2-chloro-acetyl)-3,4-dihydro-1H-isoquinolin-2-yl]-2,2,2-trifluoro-ethanone

생성물 1

HCID 441936264-Benzyloxy-1-{2-oxo-2-[2-(2,2,2-trifluoro-acetyl)-1,2,3,4-tetrahydro-isoquinolin-7-yl]-ethyl}-1H-pyridin-2-one

출처 및 근거

ORD 기록
ord-0a2720e8e2b84867a5e4d916299c1647
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

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