참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,5-Pentanediol | HCID 8105 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | gamma-Linolenoyl Chloride | HCID 11770936 | — |
| 촉매 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-(z,z,z-Octadeca-6,9,12-trienoyloxy)-5-hydroxypentane | HCID 86758952 | — |
반응 단계
z,z,z-Octadeca-6,9,12-trienoyl chloride (2 g) was added dropwise to a solution of 1,5-dihydroxypentane (3.5 g), triethylamine (0.94 ml) and 4-(N,N-dimethylamino)pyridine (0.2 g) in methylene chloride (50 ml) with stirring at 0° C. under nitrogen. On completion of reaction as evidenced by tic the reaction mixture was washed with dilute hydrochloric acid and water, dried and purified by column chromatography yielding 1-(z,z,z-octadeca-6,9,12-trienoyloxy)-5-hydroxypentane as a pale yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | USRE040480E1 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-cbcdcbb4942040c9a316d6870efd219d |
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| 출처 메모 | uspto-grants-2008_09 |
|---|
