Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydroquinone → 4-(6-(2-Tetrahydropyranyl)oxyhexyloxy)phenol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydroquinone | HCID 785 | — |
| 반응물 | Potassium Iodide | HCID 4875 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-(6-Chlorohexyloxy)tetrahydro-2H-pyran | HCID 329803 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 4-(6-(2-Tetrahydropyranyl)oxyhexyloxy)phenol | HCID 17838576 | 82.5% |
반응 단계
A mixture of 10 g of 2-(6-chlorohexyloxy)tetrahydropyrane, 25 g of hydroquinone, 31 g of potassiumcarbonate, 0.752 g of potassiumiodide and 250 ml of dimethylsulfoxide was allowed to react for 4 days at 80° C. Subsequently, the reaction mixture was cooled to room temperature and after addition of water extracted with ether. The organic phase was then dried over sodium sulphate, filtered and concentrated to dryness. Chromatography on silica with 10% ethylacetate in toluene gave 11 g of product as a yellowish oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419620B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-7f83b244a5014c8fbe2f48fda79a83a5 |
| 출처 메모 | uspto-grants-2008_09 |