3-Benzyloxycarbonylamino-5,5-dimethyl-octanoic acid tert-butyl ester → (S)-3-Amino-5,5-dimethyl-octanoic acid tert-butyl ester

HRID 28440노트

반응식

HRID 28440 반응식
[C:1]([O:5][C:6](=[O:27])[CH2:7][CH:8]([NH:16]C(OCC1C=CC=CC=1)=O)[CH2:9][C:10]([CH3:15])([CH3:14])[CH2:11][CH2:12][CH3:13])([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:27])[CH2:7][C@@H:8]([NH2:16])[CH2:9][C:10]([CH3:15])([CH3:14])[CH2:11][CH2:12][CH3:13])([CH3:3])([CH3:2])[CH3:4]

참가 물질

3

반응물 1

HCID 688548473-Benzyloxycarbonylamino-5,5-dimethyl-octanoic acid tert-butyl ester

생성물 1

HCID 86589982(S)-3-Amino-5,5-dimethyl-octanoic acid tert-butyl ester

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

According to example 1, 1.63 g of 3-benzyloxycarbonylamino-5,5-dimethyl-octanoic acid tert-butyl ester and 0.2 g of 20% Pd/C furnished the title compound. MS, m/z, 244.2 (M+1)+.

출처 및 근거

ORD 기록
ord-d56c13b254b24d9ebc87a01d5f536021
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07419981B2

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