Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyrrolidine → 1-(1,3-Dioxobutyl)pyrrolidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyrrolidine | HCID 31268 | — |
| 반응물 | Diketene acetone | HCID 87118046 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 1-(1,3-Dioxobutyl)pyrrolidine | HCID 100722 | 97.9% |
반응 단계
9 ml (0.05 mol) of diketene-acetone adduct and a solution of 4.2 ml (0.05 mol) of pyrrolidine in 20 ml of toluene were treated as described in preparation 7. The solvent was removed in vacuo and the residue was purified by chromatography on silica gel (EtOAc/MeOH 0%→1%) yielding 7.6 g of the title compound as a dark oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731322 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-fc50405695d1443a80eda06a3dd99d45 |
| 출처 메모 | uspto-grants-1998_03 |