Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminophenethyl alcohol → 2-{4-[2-Amino-6-(2,5-dimethyl-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminophenethyl alcohol | HCID 66904 | — |
| 반응물 | 4-Chloro-6-(2,5-dimethyl-phenyl)-pyrimidin-2-yl-amine | HCID 86594602 | — |
| 생성물 | 2-{4-[2-Amino-6-(2,5-dimethyl-phenyl)-pyrimidin-4-ylamino]-phenyl}-ethanol | HCID 11256113 | — |
반응 단계
Following the method described in Example 4, 4-chloro-6-(2,5-dimethyl-phenyl)-pyrimidin-2-yl-amine and 4-aminophenethyl alcohol provided the title compound as hydrochloride salt (85% yield). 1H NMR (DMSO-d6) δ 2.29 (s, 6H, CH3), 6.30 (s, 1H, Ar), 7.24-7.31 (m, 5H, Ar), 7.68 (d, 2H, J=8.0 Hz, Ar), 10.67 (s, 1H), 12.54 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419984B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-1ae65515b940409bbc78a6d91052e995 |
| 출처 메모 | uspto-grants-2008_09 |