Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,2,2-Trifluoroethyl trifluoromethanesulfonate → 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,2,2-Trifluoroethyl trifluoromethanesulfonate | HCID 80366 | — |
| 반응물 | 2-Bromo-4-chloro-1-(2,2,2-trifluoro-ethoxy)-benzene 4-bromo-phenol | HCID 86594603 | — |
| 생성물 | 1-Bromo-4-(2,2,2-trifluoroethoxy)benzene | HCID 22913883 | 40% |
반응 단계
Following the method described in Example 89 for the synthesis of 2-bromo-4-chloro-1-(2,2,2-trifluoro-ethoxy)-benzene 4-bromo-phenol and trifluoro-methanesulfonic acid 2,2,2-trifluoro-ethyl ester gave 1-bromo-4-(2,2,2-trifluoro-ethoxy)-benzene (40% yield). 1H NMR (acetone-d6) δ 4.68 (q, 2H, J=8.5 Hz, CH2), 7.04 (d, 2H, J=9.1 Hz, Ar), 7.49 (d, 2H, J=9.1 Hz, Ar).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419984B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-c912224cf53a4801a4416a5bc234448f |
| 출처 메모 | uspto-grants-2008_09 |