Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Bromide → 4-(2-Benzyloxy-5-chloro-phenyl)-6-chloro-pyrimidin-2-ylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | 2-(2-Amino-6-chloro-pyrimidin-4-yl)-4-chloro-phenol | HCID 136341889 | — |
| 생성물 | 4-(2-Benzyloxy-5-chloro-phenyl)-6-chloro-pyrimidin-2-ylamine | HCID 86004387 | 56% |
반응 단계
Following the method described in Example 72, 2-(2-amino-6-chloro-pyrimidin-4-yl)-4-chloro-phenol and bromomethyl-benzene provided 4-(2-benzyloxy-5-chloro-phenyl)-6-chloro-pyrimidin-2-ylamine (56% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419984B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-55df34c9fbad45928bdd8945f193897f |
| 출처 메모 | uspto-grants-2008_09 |