Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Toluidine → 6-[5-Bromo-2-(2-methoxy-benzyloxy)-phenyl]-N*4*-p-tolyl-pyrimidine-2,4-diamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Toluidine | HCID 7813 | — |
| 반응물 | HCID 178489517 | HCID 178489517 | — |
| 생성물 | 6-[5-Bromo-2-(2-methoxy-benzyloxy)-phenyl]-N*4*-p-tolyl-pyrimidine-2,4-diamine | HCID 42606990 | 36% |
반응 단계
Following the method described in Example 4, 6-[5-bromo-2-(2-methoxy-benzyloxy)-phenyl]-6-chloro-pyrimidin-2-ylamine and 4-methyl-phenylamine provided the title compound (36% yield). 1H NMR (CD3OD) δ 3.82 (s, 3H, CH3), 5.25 (s, 2H, CH2), 6.32 (s, 1H, Ar), 6.89-6.98 (m, 2H, Ar), 7.21-7.30 (m, 6H, Ar), 7.59-7.72 (m, 3H, Ar).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419984B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-f7275f0f88e743ceab141c46b63b009a |
| 출처 메모 | uspto-grants-2008_09 |