Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-chlorophenyl-2-[4-(2-phenylpropyl)piperazin-1-yl]ethylcyclohexanol Dihydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Phenylpropanal | HCID 7146 | — |
| 반응물 | 1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol | HCID 10381502 | — |
| 반응물 | 1-{1-(3-Chlorophenyl)-2-[4-(2-phenylpropyl)piperazin-1-yl]ethyl}cyclohexanol dihydrochloride | HCID 11249288 | — |
| 생성물 | 3-chlorophenyl-2-[4-(2-phenylpropyl)piperazin-1-yl]ethylcyclohexanol Dihydrochloride | HCID 86600406 | — |
반응 단계
In an analogous manner to Example 117, 1-{1-(3-chlorophenyl)-2-[4-(2-phenylpropyl)piperazin-1-yl]ethyl}cyclohexanol dihydrochloride was prepared from 1-[1-(3-chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol (see Example 1) and 2-phenylpropionaldehyde. MS (ESI) m/z 441/443 ([M+H]+); HRMS: calcd for C27H37ClN2O.2.00 HCl, 512.2128; found (ESI), 441.2662.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07419980B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-4df71547f8b34476aa219a6c6686f85e |
| 출처 메모 | uspto-grants-2008_09 |