Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Cyanide → 4-(7-Methoxy-1-naphthyl)butyronitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Cyanide | HCID 9032 | — |
| 반응물 | 3-(7-Methoxy-1-naphthyl)propyl mesylate | HCID 15336867 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-(7-Methoxy-1-naphthyl)butyronitrile | HCID 15336868 | — |
반응 단계
In a 100-cm3 flask, the 3-(7-methoxy-1-naphthyl)propyl mesylate obtained in stage D is dissolved in DMSO. KCN is added and the mixture is brought to reflux for 2 h. It is allowed to cool. It is poured into a water/ice mixture. The resulting mixture is extracted with ether. The organic phase is washed with water, dried over CaCl2 and evaporated. The product obtained is recrystallized.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731352 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-ebf01e6b38bc42c089b9940d05b2423f |
| 출처 메모 | uspto-grants-1998_03 |