Methyl DL-leucinate hydrochloride → Methyl 2-[[6-(cyclopentylmethoxy)-5-(4,4-difluoropiperidin-1-yl)pyrazine-2-carbonyl]amino]-4-methylpentanoate

HRID 289859

반응식

HRID 289859 반응식
[CH3:50][O:51][C:52]([CH:53]([NH2:54])[CH2:55][CH:56]([CH3:57])[CH3:58])=[O:59].[CH:26]1([CH2:31][O:32][c:33]2[c:34]([N:42]3[CH2:43][CH2:44][C:45]([F:48])([F:49])[CH2:46][CH2:47]3)[n:35][cH:36][c:37]([C:39](=[O:40])[OH:41])[n:38]2)[CH2:27][CH2:28][CH2:29][CH2:30]1.[OH:1][CH2:2][CH:3]([NH:4][C:5]([c:6]1[cH:7][n:8][c:9]([N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[c:15]([O:16][CH2:17][CH2:18][CH3:19])[n:20]1)=[O:21])[CH2:22][CH:23]([CH3:24])[CH3:25]>>[CH:26]1([CH2:31][O:32][c:33]2[c:34]([N:42]3[CH2:43][CH2:44][C:45]([F:48])([F:49])[CH2:46][CH2:47]3)[n:35][cH:36][c:37]([C:39](=[O:40])[NH:54][CH:53]([C:52]([O:51][CH3:50])=[O:59])[CH2:55][CH:56]([CH3:57])[CH3:58])[n:38]2)[CH2:27][CH2:28][CH2:29][CH2:30]1

참가 물질

4

반응물 3

HCID 410817Methyl DL-leucinate hydrochlorideHCID 685665716-Cyclopentylmethoxy-5-(4,4-difluoro-piperidin-1-yl)-pyrazine-2-carboxylic acidHCID 178458939HCID 178458939, 화합물

생성물 1

HCID 68567475Methyl 2-[[6-(cyclopentylmethoxy)-5-(4,4-difluoropiperidin-1-yl)pyrazine-2-carbonyl]amino]-4-methylpentanoate

출처 및 근거

ORD 기록
ord-4ab3daf6042e4eec905445a46affd682
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

연결된 노트

불러오는 중…