Tetrahydrofuran → Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate

HRID 291268

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][CH:15]=[C:16]([Br:17])[Br:18])[CH2:12][CH2:13]1.[CH2:19]([Li:20])[CH2:21][CH2:22][CH3:23].[CH2:24]1[O:25][CH2:26][CH2:27][CH2:28]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][C:15]#[CH:16])[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 8028Tetrahydrofuran

HCID 15503387Tert-butyl 4-(3,3-dibromoallyl)piperidine-1-carboxylate

HCID 178418339Butyllithium

생성물 1

HCID 18187546Tert-butyl 4-(prop-2-yn-1-yl)piperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-fab5abf32f134dc7938643b27ddba628
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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