[2-Amino-5-(tetrahydro-pyran-2-yloxymethyl)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester → [2-{3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-(tetrahydro-pyran-2-yloxymethyl)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:26])[cH:10][c:11]([C:22]([F:23])([F:24])[F:25])[c:12]([CH2:14][O:15][CH:16]2[O:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:13]1)=[O:27].[C:28]([CH3:30])([CH3:31])([O:32][C:33](=[O:29])[CH2:34][C:35](=[O:36])[c:37]1[cH:38][c:39](-[c:43]2[cH:44][c:45]([CH3:49])[n:46][cH:47][cH:48]2)[cH:40][cH:41][cH:42]1)[CH3:50]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:26][C:33](=[O:32])[CH2:34][C:35](=[O:36])[c:37]2[cH:38][c:39](-[c:43]3[cH:44][c:45]([CH3:49])[n:46][cH:47][cH:48]3)[cH:40][cH:41][cH:42]2)[cH:10][c:11]([C:22]([F:23])([F:24])[F:25])[c:12]([CH2:14][O:15][CH:16]2[O:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:13]1)=[O:27]