Methyl Acetate → {3-[2-(2,4-Dichloro-benzoyl)3-methyl-benzofuran-6-yl]-phenyl}-acetic acid methyl ester

HRID 29255

반응식

Br[C:2]1[CH:21]=[CH:20][C:5]2[C:6]([CH3:19])=[C:7]([C:9]([C:11]3[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=3[Cl:18])=[O:10])[O:8][C:4]=2[CH:3]=1.[CH3:22][O:23][C:24](=[O:26])[CH3:25]>>[CH3:22][O:23][C:24](=[O:26])[CH2:25][C:2]1[CH:21]=[CH:20][CH:5]=[C:4]([C:2]2[CH:21]=[CH:20][C:5]3[C:6]([CH3:19])=[C:7]([C:9](=[O:10])[C:11]4[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=4[Cl:18])[O:8][C:4]=3[CH:3]=2)[CH:3]=1

참가 물질

반응물 2

HCID 6584Methyl Acetate

HCID 59788907(6-Bromo-3-methyl-benzofuran-2-yl)(2,4-dichloro-phenyl)methanone

생성물 1

HCID 59788899{3-[2-(2,4-Dichloro-benzoyl)3-methyl-benzofuran-6-yl]-phenyl}-acetic acid methyl ester

실험 절차

{3-[2-(2,4-Dichloro-benzoyl)-3-methyl-benzofuran-6-yl]-phenyl}-acetic acid methyl ester was prepared via a Suzuki coupling of (6-Bromo-3-methyl-benzofuran-2-yl)-(2,4-dichloro-phenyl)-methanone and 3-Bromo-phenyl)-acetic acid methyl ester as described in method 1 step 5. MS ES (MH+)453.1, RT=4.27 min).

출처 및 근거

ORD 기록: ord-a588b0422ee0410ab0ab9e31a6bd2112
출처 데이터셋: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07420066B2

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