참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Amino-4-methylphenol | HCID 7264 | — |
| 반응물 | Ethyl 2,2,2-triethoxyacetate | HCID 5090273 | — |
| 생성물 | 5-Methyl-benzooxazole-2-carboxylic acid ethyl ester | HCID 68713060 | 91% |
반응 단계
To 2-amino-4-methylphenol (1 g, 8.1 mmol) was added ethyl triethoxyacetate (5.4 g, 3 eq). The mixture was stirred at 110° C. overnight. The reaction mixture was cooled and triturated with hexane. Filtration gave 850 mg (91%) of 5-methyl-benzooxazole-2-carboxylic acid ethyl ester as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07420001B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-8b7b0d44b47645e18d89b4e26aef221a |
|---|
| 출처 메모 | uspto-grants-2008_09 |
|---|
