참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-Amino-4-(trifluoromethyl)benzenethiol | HCID 88042 | — |
| 반응물 | Ethyl 2,2,2-triethoxyacetate | HCID 5090273 | — |
| 생성물 | Ethyl 5-(trifluoromethyl)-2-benzothiazolecarboxylate | HCID 55189808 | — |
반응 단계
To 2-amino-4-trifluoromethyl-benzenethiol (0.7 g) was added ethyl triethoxyacetate (3 eq). The mixture was stirred at 110° C. overnight. The reaction mixture was cooled and triturated with hexane. Filtration gave 460 mg of 5-trifluoromethyl-benzothiazole-2-carboxylic acid ethyl ester as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07420001B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-0b562ebc862241489a596e1f9fcc353b |
|---|
| 출처 메모 | uspto-grants-2008_09 |
|---|
