Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Acetate → 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Acetate | HCID 517045 | — |
| 반응물 | Rhodanine | HCID 1201546 | — |
| 반응물 | 3,5-Di-(2-propenyl)-4-hydroxybenzaldehyde | HCID 12047778 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 5-[(3,5-Di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone | HCID 54005288 | 94.6% |
반응 단계
3,5-di-(2-propenyl)-4-hydroxybenzaldehyde (50.5 g), 36.6 g of rhodanine and 164 g of sodium acetate were heated together at reflux temperature in 1.25 liter of acetic acid for 14.5 hours. The resultant solution was cooled, poured into 2 liter of ice water to yield, upon separation, about 75 g of 5-[(3,5-di-2-propenyl-4-hydroxyphenyl)-methylene]-2-thioxo-4-thiazolidinone, m.p. 157°-160° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731336 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-0c27d491eec04e228dfd3d1e3bf80bcf |
| 출처 메모 | uspto-grants-1998_03 |