Nitric Acid → 4'-Nitro-4-biphenylsulfonic acid

HRID 29493

반응식

HRID 29493 반응식
[C:1]1([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:6]=[CH:5][C:4]([S:7]([OH:10])(=[O:9])=[O:8])=[CH:3][CH:2]=1.FC(F)(F)C(O)=O.[N+:24]([O-])([OH:26])=[O:25]>>[N+:24]([C:14]1[CH:15]=[CH:16][C:11]([C:1]2[CH:6]=[CH:5][C:4]([S:7]([OH:10])(=[O:8])=[O:9])=[CH:3][CH:2]=2)=[CH:12][CH:13]=1)([O-:26])=[O:25]

참가 물질

4

반응물 3

HCID 944Nitric AcidHCID 6422Trifluoroacetic acidHCID 16673(1,1'-Biphenyl)-4-sulfonic acid

생성물 1

HCID 534258824'-Nitro-4-biphenylsulfonic acid

반응 조건

온도
-5 °C

실험 절차

Biphenyl-4-sulfonic acid (30 g) was mixed with trifluoroacetic acid and a suspension was formed. The mixture was cooled to −5° C. Fuming nitric acid (12.8 ml) was added dropwise over 30 min. The reaction mixture was stirred at 0° C. for 2 h. The chloroform was removed in vacuo and the residue was recrystallized from acetic acid to provide 15 g of 4′-nitro-biphenyl-4-sulfonic acid, obtained as white crystals.

후처리

  1. customa suspension was formed
  2. customThe chloroform was removed in vacuo
  3. customthe residue was recrystallized from acetic acid

출처 및 근거

ORD 기록
ord-c85642210abd41d89146536782ef2f01
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07420001B2

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