참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2-Tert-Butylphenol | HCID 6923 | — |
| 반응물 | Allyl bromide | HCID 7841 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-(1,1-Dimethylethyl)phenoxypropene | HCID 67631224 | — |
반응 단계
Allyl bromide (69.2 ml), 2-t-butylphenol (122.9 ml) and potassium carbonate (121.6 g) were stirred in 265 ml of acetone at reflux temperature for 50 hours and then cooled to 35° C. Water (600 ml) was added and the resulting layers were separated. The aqueous layer was extracted with 600 ml of diethyl ether. The organic layer was combined with the aqueous layer's ether extract and the resulting solution was dried over sodium sulfate overnight. After sodium sulfate removal, the solvent was evaporated to provide, after further workup, 147 g of the subtitled intermediate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US05731336 |
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| 출처 데이터셋 | uspto-grants-1998_03 |
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| ORD ID | ord-f43f465340624f4daaa306b11664c6ec |
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| 출처 메모 | uspto-grants-1998_03 |
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