Dichloromethane → Tert-butyl 4-[[[6-butyl-5-(4-cyclohexyloxyphenyl)pyridazine-3-carbonyl]amino]methyl]-3-fluoropiperidine-1-carboxylate

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([F:16])[CH:11]([CH2:14][NH2:15])[CH2:12][CH2:13]1.[Cl:54][CH2:55][Cl:56].[F:17][c:18]1[c:19]([O:24][C:25](=[O:20])[c:27]2[n:28][n:29][c:30]([CH2:46][CH2:47][CH2:48][CH3:49])[c:31](-[c:33]3[cH:34][cH:35][c:36]([O:39][CH:40]4[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]4)[cH:37][cH:38]3)[cH:32]2)[c:21]([F:22])[c:23]([F:26])[c:50]([F:51])[c:52]1[F:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([F:16])[CH:11]([CH2:14][NH:15][C:25](=[O:24])[c:27]2[n:28][n:29][c:30]([CH2:46][CH2:47][CH2:48][CH3:49])[c:31](-[c:33]3[cH:34][cH:35][c:36]([O:39][CH:40]4[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]4)[cH:37][cH:38]3)[cH:32]2)[CH2:12][CH2:13]1