Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
p-Bromobenzenesulfonyl chloride → 4-Bromo-N-[4-chloro-2-(pyridine-4-carbonyl)-phenyl]-benzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | p-Bromobenzenesulfonyl chloride | HCID 7396 | — |
| 반응물 | (2-Amino-5-chlorophenyl)-pyridin-4-yl methanone | HCID 10214538 | — |
| 생성물 | 4-Bromo-N-[4-chloro-2-(pyridine-4-carbonyl)-phenyl]-benzenesulfonamide | HCID 10072530 | — |
반응 단계
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone and 122 mg of 4-bromo-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 7.21 (d,1H, J=2.4 Hz), 7.49-7.61 (m, 5H), 7.73 (d,1H, J=8.8 Hz), 8.86 (dd, 2H, J=4.4 Hz, 1.2 Hz), 10.00 (s, 1H). MS: m/z 451.9 (M++1)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07420055B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-44d9851ed22a46c19d30f458d4fd14c2 |
| 출처 메모 | uspto-grants-2008_09 |