Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formic Acid → N-formylphenylalanine methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formic Acid | HCID 284 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | N-formylphenylalanine methyl ester | HCID 7016392 | — |
반응 단계
To a mixture of 1 mmol of phenylalanine methyl ester hydrochloride and 2 mmol of triethylamine in 1 mL of DMF at 0 ° C. was added 2 mL of formic acid and 0.7 mL of acetic anhydride. After stirring for 16 h at rt, extractive isolation provided N-formylphenylalanine methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731432 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-2f2ad81b1f6b433ea7c984999ad32978 |
| 출처 메모 | uspto-grants-1998_03 |