Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 3-Iodo-4-methylbenzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | 3-Iodo-4-methylbenzoic acid | HCID 621640 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Iodo-4-methylbenzyl alcohol | HCID 5166798 | — |
반응 단계
A mixture of 1.0 mmol of 3-iodo-4-methylbenzoic acid and 1.2 mmol of NaBH4 in 4 mL of anhydrous THF was stirred for 30 min and then 0.5 mmol of iodine in 2.0 mL of THF at 5° C. was added. After stirring for 2 h the mixture was processed by extraction to provide 3-iodo-4-methylbenzyl alcohol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05731432 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-2717ca80753c46a39e12e91d075435b5 |
| 출처 메모 | uspto-grants-1998_03 |