참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Tert-Butylamine | HCID 6385 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Silane, (chloromethyl)trimethyl- | HCID 75361 | — |
| 생성물 | N-tert-Butyl-N-(trimethylsilylmethyl)amine | HCID 425246 | — |
반응 단계
A mixture of tert-butylamine (18.0 mL, 171 mmol) and (chloromethyl)trimethylsilane (7.00 g, 57.1 mmol) was heated in a thick-walled glass tube at 200° C. overnight. After cooling to ambient temperature, the reaction mixture was poured into 1 N NaOH and extracted three times with diethyl ether. The combined organic extracts were washed with brine, dried (MgSO4), and the volatiles evaporated in vacuo. Distillation (atmospheric pressure; ˜135° C.) of the residual liquid gave the title compound 77 as a colorless liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07419990B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-043b0c3cc51046faa4d80dcc8ff53bfc |
|---|
| 출처 메모 | uspto-grants-2008_09 |
|---|
