3-Iodo-4-methylbenzaldehyde → 3-Iodo-4-methylstyrene

HRID 2974

반응식

HRID 2974 반응식
[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=O.[Li][CH2:12]CCC>[Br-].C[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.C1COCC1>[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=[CH2:12]

참가 물질

5

반응물 2

HCID 123302543-Iodo-4-methylbenzaldehydeHCID 178418339Butyllithium

생성물 1

HCID 196884243-Iodo-4-methylstyrene

시약·촉매·용매 2

HCID 74505Methyltriphenyliphosphonium bromide촉매HCID 8028Tetrahydrofuran용매

실험 절차

This aldehyde (1 mmol)was added to a premixed solution of 1.5 mmol of methyl triphenylphosphonium bromide and 1.2 mmol of n-BuLi in 5 mL of THF at 0° C. and this mixture was stirred for 3-6 h at rt and then processed by extraction and chromatography to give 3-iodo-4-methylstyrene.

후처리

  1. extractionprocessed by extraction and chromatography

출처 및 근거

ORD 기록
ord-e65eb05600a341c1a97cfb8e1984da81
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05731432

연결된 노트

불러오는 중…