3-Iodo-4-methylbenzaldehyde → 3-Iodo-4-methylstyrene
반응식
[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=O.[Li][CH2:12]CCC>[Br-].C[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1.C1COCC1>[I:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[CH3:10])[CH:5]=[CH2:12]참가 물질
5
실험 절차
This aldehyde (1 mmol)was added to a premixed solution of 1.5 mmol of methyl triphenylphosphonium bromide and 1.2 mmol of n-BuLi in 5 mL of THF at 0° C. and this mixture was stirred for 3-6 h at rt and then processed by extraction and chromatography to give 3-iodo-4-methylstyrene.
후처리
- extractionprocessed by extraction and chromatography
출처 및 근거
- ORD 기록
- ord-e65eb05600a341c1a97cfb8e1984da81
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05731432
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