Dimethylformamide → HCID 178418432, 화합물

참여 물질

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A mixture of 1 mmol of 3-(3'-carbobenzyloxypropyl)coformycin aglycone and10 mg of 10% Pd/C in 4 mL of methanol was subjected to hydrogenation. After filtration and removal of the solvent, 3-(3'-carboxypropyl)coformycin aglycone was obtained. This product, 2 mmol glycine ethyl ester hydrochloride, 2 mmol triethylamine, 2 mmol dicyclohexylcarbodiimide and 2 mmol N-hydroxysuccinimide in 10 mL DMF were stirred 16 h and filtered. Chromatography provided N-(4-(3,6,7,8-tetrahydro-imidazo[4,5-d]-[1,3]diazepin-8-ol-3-yl)butyryl)glycine ethyl ester.

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