Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → methyl 3-[N'-benzyloxycarbonyl-hydrazinocarbonyl)-benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Benzyl carbazate | HCID 79242 | — |
| 반응물 | Methyl 3-(chlorocarbonyl)benzoate | HCID 15563901 | — |
| 용매 | Pyridine | HCID 1049 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | methyl 3-[N'-benzyloxycarbonyl-hydrazinocarbonyl)-benzoate | HCID 12571328 | — |
반응 단계
10.80 g (54.4 mmol) methyl 3-chlorocarbonyl-benzoate in 100 mL diethyl ether are added dropwise to a solution of 9.04 g (54.4 mmol) benzyl hydrazine carboxylate in 100 mL diethyl ether, 100 mL dichloromethane and 4.83 mL pyridine while cooling with an ice bath. The reaction mixture is stirred overnight at ambient temperature and then combined with water. The precipitated solid is filtered off and washed with diethyl ether. White solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423036B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-a1590d231f5e491abba1d3b8bec6d5a0 |
| 출처 메모 | uspto-grants-2008_09 |