4-Chlorobenzohydrazide → HCID 178465662, 화합물
반응식
C[O-].[Na+].Cl.[C:5]([NH2:8])(=[NH:7])[CH3:6].[Cl:9][C:10]1[CH:19]=[CH:18][C:13]([C:14]([NH:16]N)=[O:15])=[CH:12][CH:11]=1>C(O)C>[NH:7]=[C:5]([NH:8][NH:16][C:14](=[O:15])[C:13]1[CH:18]=[CH:19][C:10]([Cl:9])=[CH:11][CH:12]=1)[CH3:6]참가 물질
5
실험 절차
1.09 g (20 mmol) sodium methoxide in 20 mL ethanol are added to a solution of 1.91 g (20 mmol) acetamidine hydrochloride in 30 mL ethanol. The mixture is stirred for 30 minutes at ambient temperature and then filtered. The filtrate is combined with 2.3 g (13.5 mmol) 4-chlorobenzoic acid hydrazide, stirred overnight at ambient temperature, cooled with an ice bath and then filtered. The precipitate is washed with cold ethanol and dried. Yellow solid. Yield: 1.45 g (51%); mass spectroscopy [M+H]+=212/214.
후처리
- filtrationfiltered
- stirringstirred overnight at ambient temperature
- temperaturecooled with an ice bath
- filtrationfiltered
- washThe precipitate is washed with cold ethanol
- customdried
출처 및 근거
- ORD 기록
- ord-496ee62380ad4f8f9002a4d76b272e6b
- 출처 데이터셋
- uspto-grants-2008_09
- 특허 번호
- US07423036B2
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