Ethyl 1-benzyl-4-oxopiperidine-3-carboxylate → HCID 178517513, 화합물

HRID 29894

반응식

HRID 29894 반응식
C(O[C:4]([CH:6]1[C:11](=O)[CH2:10][CH2:9][N:8]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH2:7]1)=[O:5])C.Cl.[Cl:21][C:22]1[CH:23]=[C:24]([CH:28]=[C:29]([Cl:31])[CH:30]=1)[C:25]([NH2:27])=[NH:26]>>[CH2:13]([N:8]1[CH2:9][CH2:10][C:11]2[N:27]=[C:25]([C:24]3[CH:28]=[C:29]([Cl:31])[CH:30]=[C:22]([Cl:21])[CH:23]=3)[N:26]=[C:4]([OH:5])[C:6]=2[CH2:7]1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

참가 물질

3

반응물 2

HCID 102624Ethyl 1-benzyl-4-oxopiperidine-3-carboxylateHCID 27431593,5-Dichlorobenzimidamide hydrochloride

생성물 1

HCID 178517513HCID 178517513, 화합물

실험 절차

The title compound was prepared from 1-benzyl-4-oxo-piperidine-3-carboxylic acid ethyl ester and 3,5-dichloro-benzamidine hydrochloride according to general procedure 1. 1H NMR (DMSO-d6, 400 MHz) δ 2.70-2.90 (m, 4H), 3.20-3.50 (m, 4H), 3.70-3.90 (m, 2H), 7.10-7.50 (m, 6H), 7.83 (s, 1H), 8.12 (s, 2H), 12.70 (br s, 1H); MS: m/z (ESI) 386 (M+H).

출처 및 근거

ORD 기록
ord-c8ee733cb6d249628a454a61ee76aa36
출처 데이터셋
uspto-grants-2008_09
특허 번호
US07423044B2

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