Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 4-(bromomethyl)benzoate → 4-({[2-(4-Chlorophenyl)-6-phenylpyrimidin-4-yl]oxy}methyl)benzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 4-(bromomethyl)benzoate | HCID 256687 | — |
| 반응물 | HCID 178515558 | HCID 178515558 | — |
| 생성물 | 4-({[2-(4-Chlorophenyl)-6-phenylpyrimidin-4-yl]oxy}methyl)benzoic acid | HCID 69197248 | — |
반응 단계
The title compound was prepared from 2-(4-chloro-phenyl)-6-phenyl-pyrimidin-4-ol (which was obtained in Intermediate 1) and methyl 4-(bromomethyl)benzoate according to Method A and Method B; 1H NMR (DMSO-d6, 300 MHz) δ 5.61 (s, 2H), 7.26 (t, J=9.0 Hz, 2H), 7.45-7.70 (m, 8H), 8.25-8.35 (m, 2H), 8.55 (d, J=6.0 Hz, 2H); LC retention time 3.86 min; MS: m/z (ESI) 415 (M−H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423044B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-91b7c6a3183541e5a89476a26877f28d |
| 출처 메모 | uspto-grants-2008_09 |