Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Bromomethyl)-4-(trifluoromethyl)benzene → 6-Benzyl-2-(3,5-dichlorophenyl)-4-{[4-(trifluoromethyl)benzyl]oxy}-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| 반응물 | HCID 178517513 | HCID 178517513 | — |
| 생성물 | 6-Benzyl-2-(3,5-dichlorophenyl)-4-{[4-(trifluoromethyl)benzyl]oxy}-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine | HCID 69198134 | — |
반응 단계
The title compound was prepared from 6-benzyl-2-(3,5-dichloro-phenyl)-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-4-ol (which was obtained in Intermediate 7) and 4-(trifluoromethyl)benzyl bromide according to Method A; LC retention time 3.49 min; MS: m/z (ESI) 544 (M+H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07423044B2 |
| 출처 데이터셋 | uspto-grants-2008_09 |
| ORD ID | ord-e6f15f64472c4ca78d6d8284e09f210f |
| 출처 메모 | uspto-grants-2008_09 |