Pyridine → methyl 5-[1-(4-fluorophenyl)-5a-methyl-6,7,8,9-tetrahydro-5H-imidazo[1,5-b]isoquinoline-6-carbonyl]thiophene-2-carboxylate

반응식

[CH2:39]([Cl:40])[Cl:41].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][n:11]3[c:20]2[CH:19]=[C:18]2[C:13]([CH3:32])([CH2:12]3)[CH:14]([CH:21]([c:22]3[cH:23][cH:24][c:25]([C:27](=[O:28])[O:29][CH3:30])[s:26]3)[OH:31])[CH2:15][CH2:16][CH2:17]2)[cH:6][cH:7]1.[cH:33]1[cH:34][cH:35][n:36][cH:37][cH:38]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][n:11]3[c:20]2[CH:19]=[C:18]2[C:13]([CH3:32])([CH2:12]3)[CH:14]([C:21]([c:22]3[cH:23][cH:24][c:25]([C:27](=[O:28])[O:29][CH3:30])[s:26]3)=[O:31])[CH2:15][CH2:16][CH2:17]2)[cH:6][cH:7]1

참가 물질

반응물 3

HCID 1049Pyridine

HCID 6344Dichloromethane

HCID 178497955HCID 178497955, 화합물

생성물 1

HCID 178497954methyl 5-[1-(4-fluorophenyl)-5a-methyl-6,7,8,9-tetrahydro-5H-imidazo[1,5-b]isoquinoline-6-carbonyl]thiophene-2-carboxylate

출처 및 근거

ORD 기록: ord-6d40bb06817f48d39c34e792b6d58c79
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

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